Current composition of the Governing Board is:
| Prof. G Rangarajan, Director, IISc – Chair |
| Shri. Kris Gopalakrishnan, Co-founder of Infosys |
| Mrs. Sudha Gopalakrishnan, Co-founder of Pratiksha Trust |
| Shri. Dinesh Krishnaswamy, Co-founder of Infosys |
| Shri. S D Shibulal, Co-founder of Infosys |
| Prof. Y Narahari, Dean, Division of Electrical, Electronics, and Computer Sciences, IISc |
| Prof. Navakanta Bhat, Dean, Division of Interdisciplinary Sciences, IISc |
| Prof. Usha Vijayraghavan, Dean, Division of Biological Sciences, IISc |
| Prof. H P Khincha, Former chairman, Division of Electrical Sciences, IISc |
| Prof. D N Rao, Former chairman, Division of Biological Sciences, IISc |
| Prof. Vijayalakshmi Ravindranath, Director, Centre for Brain Research – Member-Secretary |